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Sphingomyelin synthase (SMS) is the only enzyme that synthesizes sphingomyelin from ceramide. The role of sphingomyelin synthase in epidermis is being understood, but there is no report on its role in the derm...
Hypertrophic scars (HTS) are raised, red, rigid, inflexible cell-like, and cosmetic problems precipitated due to multiple underlying dermal injuries such as burn, surgery, and trauma during which aberrant woun...
The fatty acids containing plant oils have been used as components of cosmetic formulations, and the best cosmetic function has been established for unsaturated fatty acids present in triglycerides. Many oils,...
Melanin is a pigment, which is widely distributed in organisms. In humans, melanin pigments determine eye, hair, and skin color and protect the skin from damage by ultraviolet radiation; however, immoderate di...
HIV infection and meningitis are diseases which are known to precipitate malnutrition. Skin manifestations of malnutrition are easy to identify. We tried to describe the skin manifestations of malnutrition in ...
Transdermal delivery systems have been intensively studied over the past 2 decades, with the focus on overcoming the skin barrier for more effective application of pharmaceutical and cosmetic products. Althoug...
Burns are injuries that lie on the skin or other organic tissues caused by exposures to the heat, electricity, chemicals or ionizing radiation. The present study was carried out to record temporal changes in t...
With the steadily increasing trend of functional cosmetics consumption, the public is increasingly expecting the efficacy of cosmetics, and in order to meet these consumer needs, the development of various eff...
Catechins, which are polyphenol compounds found in many plants and are an important component of tea leaves, are strong anti-oxidants.
Present research addresses the issue of skin aging and corresponding skin treatment individualization. Particular research question was on the developing of simplified criterion supporting patient-specific dec...
Using human keratinocyte HaCaT cell line model, we screened for proteins that changed their content due to SDS exposure in non-toxic dose (25 μg/ml, as determined by the MTT assay and microscopic examination) ...
Trichofolliculoma of the eyelid and periorbital region remains is rare, and there is limited evidence regarding surgical management, clinical and histological margins, and recurrence rate.
There is a significant variation in the reported prevalence of hidradenitis suppurativa (HS), ranging from 0.03–4%. We hypothesized that this significant variation may be due to different prevalence rates of H...
Recently, investigators have been trying to apply the by-products as well as stem cells themselves to various fields such as pharmaceuticals, medical devices, quasi-drug, cosmetis, etc. We aimed to comfirm the...
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder which involves painful nodules and draining abscesses in flexural areas. Acne vulgaris and its more severe variants including acne congloba...
Sunlight is one of the main harmful exogenous factors that induce the reactive oxygen species formation. The human skin is the first line of photoprotection against harmful exogenous factors, such as UV radiat...
The present research addresses the issue of skin aging and corresponding skin treatment individualization. Particular research question was on the development of a simplified criterion supporting patient-speci...
The present study aimed to investigate the anti-inflammatory activity of Helichrysum bracteatum (H. bracteatum) flower extracts in vitro.
Hair loss, known as alopecia, causes psychological stress and influences social interactions. At present, treatment for hair loss is somewhat limited, transient, and unpredictable. Based on the critical role o...
Female pattern hair loss (FPHL) is a common non-scaring alopecia. Topical minoxidil is the only approved treatment for FPHL; however, it has frequent side effects. Ketoconazole is an antifungal with anti-andro...
Ganoderma lucidum, a double-walled basidiospore produced by porous basidiomycete fungi, has been used as a traditional medicine for thousands of years. It is considered a valuable Chinese medicine for strengtheni...
Vitiligo is a frequently underestimated and little known dermal disease whose symptoms appear as white patches on several skin areas of the body. In this review, the impact of idiopathic and chemical-induced v...
Acne vulgaris is a common inflammatory skin disease, affecting adolescents across the globe. Recent evidences underline that Propionibacterium acnes (P. acnes) promotes acne through Toll-like receptor (TLR) activ...
Melanoma and acne are highly prevalent dermatological diseases. A meta-analysis of case-control studies was performed to explore obesity as a risk factor for the same.
Atopic dermatitis (AD) patients are more frequently colonized with Staphylococcus aureus. The aim of this study is to determine the prevalence of community-acquired methicillin-resistant S. aureus (CA-MRSA) colon...
Foot ulcers in diabetes mellitus subjects cause morbidity and mortality and lead to non-traumatic amputations worldwide. Knowledge of the microbial burden in the ulcers may improve patients’ care and management.
This study aims to clinically verify the effects of myrtle essential oil, which has non-irritation, non-toxicity, and non-sensitivity characteristics among natural materials, by applying the oil to acne skin o...
6-Shogaol is a constituent of ginger that imparts the pungent flavor and a hydrolysis product of gingerols. This study aimed to investigate the potential of 6-shogaol as a natural cosmetic raw material by exam...
This study aims to investigate the ability of naringenin to regulate the expression of nuclear factor-кB, the upper gene of lipopolysaccharide-induced SIRT1; regulate signal transduction in the extracellular m...
Chemical peeling is increasingly used in dermatology nowadays. Salicylic acid peels have been widely used in Asian patients since long ago, but very few published literature is there focusing on the efficacy a...
The development of the beauty industry has been accelerated by the combination of the basic desire of humans to look beautiful and the trend of the age in which the down-aging phenomenon is caused by an aging ...
Hair follicle morphogenesis is orchestrated by bidirectional ectodermal–mesenchymal signaling. In particular, TGFβ (transforming growth factor-beta) family is an important regulator of hair follicle formation ...
Hyaluronic acid (HA) filler is the most commonly used filler for soft tissue augmentation. There are numerous commercially available HA fillers in the cosmetic market, and there are guidelines for each filler ...
Vitiligo is a common dermatological disorder of chronic depigmentation which is phenotypically characterized by white macules on the skin caused as a result of the systematic destruction of functional melanocy...
Hydroxytyrosol is discovered in a form of elenolic acid ester oleuropein in olive leaf and oil. The anti-carcinogenic, antioxidant, and anti-inflammatory effects of hydroxytyrosol have been reported in the foo...
Skin is a complex ecosystem hosting a diverse microbial population as well as distinct environmental niches leading to hundreds of skin conditions that affect humans. There is an evident shift towards the meta...
The interaction of genetic variants and their distribution in the genome is firmly believed to contribute to genetic dermatological disorders. For the convenience of clinicians and researchers to explore such ...
The exact pathogenesis of vitiligo is still unclear; however, studies mostly support autoimmune mechanisms including altered T-regulatory cells and FOXP3. C-Rel is a NF-κB family member affecting the normal de...
Syringic acid is a phenolic compound that can be produced through selective hydrolysis of eudesmic acid containing 20% sulfuric acid. The acid is obtained by breaking down components, such as anthocyanin and l...
The flavonoid prunin is a flavanone glycoside found in cherry trees, including the flowering cherry Prunus yedoensis Matsumura (Rosacea). Although this compound has been studied for its antioxidant, anti-bacteria...
This study examines the cellular protective effects of scutellarin on HaCaT cells in which oxidative stress was induced by ultraviolet A (UVA).
Phytol is a component of chlorophyll with demonstrated anticancer and immune-enhancing effects. In particular, it has been reported that phytol enhances the activity of natural killer cells that detect and rem...
Morin is a family of phenolic compounds and is a bioflavonoid ingredient in fruits and vegetables. Morin exhibits various biological activities, including antioxidant cell protection and antimutagenic and anti...
Embelin is a major active ingredient of Embelia ribes Burm. belonging to Myrsinaceae, an important traditional medicinal plant of Indian origin. Embelin has a benzoquinone derivative structure and has been studie...
Sinapic acid is a phenolic compound in various plants, including spices, berries, citrus fruits, vegetables, grains, and oil seeds. It has been studied mainly for the various pathological symptoms it induces r...
Injectable dermal fillers are commonly used by physicians in the treatment of the signs of aging. The most commonly used dermal filler is hyaluronic acid. Skinfill plus (SFP) belongs to the family of monophasi...
Protocatechuic acid (PCA) is an anthocyanin metabolite with a high antioxidant property. It is also known for having anticancer and anti-inflammatory capacities with diverse medicinal activities. As one of the...
Paclitaxel well known as anti-cancer drug has been shown to cause alopecia in chemotherapy. The paclitaxel chemotherapy-mediated alopecia is induced by apoptotic damage in human dermal papilla (HDP) cells. Epi...
Hand washing with soap and water is a good hand hygiene practice which reduces the chance of infection transmission through hand contact. This study was designed to determine the microbial hand carriage among ...
The causative agent of leprosy is Mycobacterium leprae (M. leprae), which establishes infectious lesions in the skin. Leprosy is classified based on the clinical manifestation, the host’s immune response and skin...