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Table 1 Activities of catechins and their applications

From: Activity of catechins and their applications

Catechin activity

Application

References

Anti-oxidant activities

Maximising the efficacy of anti-oxidants and catechins in new substances

D’Urso et al. 2018, Gallego et al. 2017, Spizzirri et al. 2009, Nadim et al. 2014, Feng et al. 2014, Feng et al. 2013, Zhong and Shahidi 2011, Muhammad et al. 2014, Li and Seeram 2018, Choi et al. 2018, Shoko et al. 2018, Lima et al. 2016

UV protection

Improve the stability of catechins in sunlight and increase the UV protection effect

Zhang et al. 2016, Yoshino et al. 2013, Niu et al. 2017, Huang et al. 2007, Martincigh and Ollengo 2016, Parisi et al. 2012, Kim et al. 2012, Xia et al. 2005

Anti-microbial activities

Demonstrates anti-microbial activity and develops pharmaceuticals and functional cosmetics

de Oliveira et al. 2017, Aoshima et al. 2009, Goyal et al. 2017

Anti-allergenic and anti-inflammatory activities

Has an anti-allergenic component and anti-inflammatory and anti-arthritic activity

Ohmori et al. 1995, Marques et al. 2018, Foyet et al. 2015, Magalhães et al. 2009

Anti-viral activities

Shows anti-influenza activity and interferes with cell infiltration and attachment of herpes simplex virus

Ide et al. 2014, Cheng 2006

Anti-cancer activities

Extract from Lawsonia inermis (Henna) can inhibit proliferation of cancer cells

Kumar et al. 2016

Activation of skin barrier passage

Various methods have enhanced the skin penetration of epigallocatechin-3-gallate (EGCG) anti-oxidants

Puri et al. 2016, Zillich et al. 2013, dal Belo et al. 2009, Kadhum et al. 2017, Bombardelli 1991, Arct et al. 2002, Yang et al. 2015c, Wisuitiprot et al. 2011

Promoting cell activities

Effective for low cytotoxicity and anti-melanin production and improves reactive oxygen species (ROS)-mediated cell viability and cell proliferation

Kim et al. 2015, Kim et al. 2018

Sludge utilisation

Anti-oxidant components were extracted from various sludge, suggesting that they could be developed into foods, cosmetics, and pharmaceuticals

Aires et al. 2016, Magalhães et al. 2015, Reis et al. 2016, Kosińska et al. 2012, Arruda et al. 2017, Hernández-Hernández et al. 2018, Sharma et al. 2013, Demoliner et al. 2018, Oliveira et al. 2013

Stability

Aspects exploited for improving stability include sunlight, oxidation, compound stability, and collagen stabilisation

Scalia et al. 2013, Ferreira-Nunes et al. 2018, Jang et al. 2014, Bianchi et al. 2011, Madhan et al. 2005, Gallego et al. 2017

Relatively stable at low pH and the extraction efficiency of anti-oxidants was high

Tsuchiya et al. 1997, Jang et al. 2014

Tissue biopsy culture model

Demonstrated efficacy in vivo and vitro culture models

Sidgwick et al. 2016, Ow and Stupans 2003, Yuki et al. 2013, Moulton et al. 2010

Safety for human applications

In vivo experiments demonstrate safety

Takahashi et al. 1999, Moulton et al. 2010

Anti-oxidant properties of catechins used for other applications

Dyes, packaging materials, nanoparticles, and biocompatibility

Im and Jeon 2016, Iñiguez-Franco et al. 2012, Kim 2011, Jeon et al. 2009, Rojas et al. 2005, Jackson et al. 2010

Synergistic effect by extraction method and process

Chemical modification, molecular interaction mechanisms, hydrogen bonding, and nanoparticle treatment increase efficiency

Ferreira-Nunes et al. 2017, Magalhães et al. 2016, Cruz et al. 2015, Yang et al. 2015a, Chen et al. 2010, Yang et al. 2015b, Niu et al. 2017, Klein et al. 2012, Skowyra et al. 2013, Arruda et al. 2019