Fig. 3

Evaluation of improvement of damaged skin by external stimuli. Skin irritation was induced by applying SLS on the upper part of both forearms of the subject using Finn Chamber. The filter paper disc was put on a Finn Chamber having a diameter of 12 mm, and 60 μL of a 2.0% SLS diluent was dripped onto the test area. The patches were attached for 24 h, and after 24 h of removal of the patches, the skin irritation was visually evaluated and measured the treated and untreated areas by analyzer before use versus after 3 weeks of use. a The measured values were obtained by analyzed the Ra value, which is a measurement variable representing the average roughness of the skin by a texture small filter and b the images were analyzed with matched area using ANTERA CS software. The paired t test was conducted to determine statistical significance(*p < 0.05)