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Fig. 4 | Biomedical Dermatology

Fig. 4

From: Anti-apoptotic, antioxidant and anti-aging effects of 6-shogaol on human dermal fibroblasts

Fig. 4

Anti-aging effect of 6-shogaol in UVA-irradiated HDFs. a 6-Shogaol inhibited cellular senescence in a dose-dependent manner. 6-Shogaol also b upregulated the expression of COL1A1 mRNA and c downregulated the expression of MMP-1 mRNA in a dose-dependent manner. The graphs are a combination of three independent experiments (mean ± S.D.). Student’s t test was conducted to determine statistical significance. *p < 0.05 compared with UVA-irradiated cells without 6-shogaol treatment; #p < 0.05 compared with negative controls that were not treated 6-shogaol or UVA irradiation

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