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Fig. 2 | Biomedical Dermatology

Fig. 2

From: Anti-apoptotic, antioxidant and anti-aging effects of 6-shogaol on human dermal fibroblasts

Fig. 2

Anti-apoptotic effect of 6-shogaol in UVA-irradiated HDFs. a Cell cycle phases were determined by the propidium iodide staining and flow cytometry. 6-Shogaol pre-treatment downregulated the number of cells in sub-G1 phase in a dose-dependent manner. b 6-Shogaol pre-treatment downregulated the expression of BAX mRNA in a dose-dependent manner. c 6-Shogaol pre-treatment downregulated the expression of caspases 3 and 9 mRNA in a dose-dependent manner. The graphs are combined from three independent experiments (mean ± S.D.). Student’s t test was conducted to determine statistical significance. *p < 0.05 compared with UVA-irradiated cells without 6-shogaol treatment; #p < 0.05 compared with negative controls that were not treated 6-shogaol or UVA irradiation

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