Fig. 4
From: Anti-inflammatory and anti-aging effects of hydroxytyrosol on human dermal fibroblasts (HDFs)
Effects of hydroxytyrosol on IL-1β mRNA (a), IL-6 mRNA (b), and IL-8 mRNA (c) expression in UVA-irradiated HDF. HDF was cultured for 24 h and pre-treated with hydroxytyrosol of different concentrations for 6 h. Afterward, the cells were irradiated with UVA for 24 h. IL-1β (a), IL-6 (b), and IL-8 (c) mRNA expression was confirmed with qRT-PCR and was found to increase with the hydroxytyrosol concentration. The graph showed the averages of three experiments with error bars representing standard deviation (*p < 0.05)