Table 3 Solvent accessibility analysis of the mutated proteins by NetSurfP
From: DermaGene and VitmiRS: a comprehensive systems analysis of genetic dermatological disorders
Genes | Type | Class assignment | Relative surface accessibility (RSA) | Z-fit score for RSA prediction |
|---|---|---|---|---|
MTHFR | Wild | B | 0.027 | 0.737 |
Mutant | B | 0.026 | 0.781 | |
TLR2 | Wild | E | 0.243 | 1.46 |
Mutant | E | 0.245 | 1.527 | |
SOD2 | Wild | B | 0.2 | − 0.736 |
Mutant | B | 0.166 | − 0.705 |