Table 2 nsSNPs found to be deleterious using I-Mutant Suite, SNPs&GO, and PANTHER
From: DermaGene and VitmiRS: a comprehensive systems analysis of genetic dermatological disorders
SNP | Genes | I-Mutant score | I-Mutant prediction | SNPs&GO score | SNPs&GO prediction | PANTHER prediction |
|---|---|---|---|---|---|---|
rs1801133 | MTHFR | − 0.78 | Disease-related mutation | 0.88 | Disease-associated variation | Probably damaging |
rs5743708 | TLR2 | − 2.78 | Disease-related mutation | 0.7 | Disease-associated variation | Possibly damaging |
rs11575993 | SOD2 | − 1.4 | Disease-related mutation | 0.66 | Disease-associated variation | Probably damaging |