Table 1 nsSNPs found to be deleterious using SIFT, PolyPhen, and PROVEAN
From: DermaGene and VitmiRS: a comprehensive systems analysis of genetic dermatological disorders
SNP | Genes | SIFT score | SIFT prediction | PolyPhen score | PolyPhen prediction | PROVEAN score | PROVEAN prediction |
|---|---|---|---|---|---|---|---|
rs1801133 | MTHFR | 0.043 | Deleterious | 0.998 | Probably damaging | 0.002 | Damaging |
rs5743708 | TLR2 | 0.016 | Deleterious | 1 | Possibly damaging | 0 | Damaging |
rs11575993 | SOD2 | 0.014 | Deleterious | 1 | Possibly damaging | 0.001 | Damaging |