Fig. 14

Protein modeling. a 3D structure of modeled mutant (R753Q) TLR2 protein. The wild-type residue is represented in green color, and the mutant residue is colored light blue. Other variants are also displayed in this structure with the dbSNP variant colored dark green, COSMIC variant colored orange, and the ClinVar variant is represented in red color. The backbone of the protein is shown in gray color. b Disease mechanism influenced by R753Q TLR2 polymorphism