Fig. 3

Senescence-attenuating effect of PCA in HDF cells. a Effect of PCA on cellular senescence was determined by SA-β-gal assay. HDF cells had been co-treated with LPS (1 μg/mL) and the indicated concentration of PCA for 24 h, then SA-β-gal assay was conducted to determine cellular senescence. b COL1A1 and c MMP1 mRNA expression were determined by qRT-PCR, and β-actin expression was used for normalization. HDF cells were treated with LPS (1 μg/mL) and the indicated concentration of PCA for 24 h. Data are expressed as mean ± standard deviation (*p < 0.05)