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Fig. 4 | Biomedical Dermatology

Fig. 4

From: Photodamage attenuation effect by angelic acid in UVA irradiation-induced damages in normal human dermal fibroblast

Fig. 4

Protective effect of angelic acid on UVA-induced cellular senescence and ECM controlling gene expression in NHDF cells. a Effect of angelic acid on cellular senescence using SA-β-gal assay. Effects of angelic acid on gene expression of b uPA, c COL1A1, and d MMP1. e Relative AP-1 promoter luciferase reporter activity using fluorescent intensity. Gene expression of uPA, COL1A1, and MMP1 was evaluated using RT-qPCR with the 2-ΔΔCt method and data presented were normalized to β-actin; *p ≤ 0.05 compared with irradiated cells without angelic acid treatment and #p ≤ 0.05 compared with negative control cells that were not treated with angelic acid and UVA irradiation

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