Fig. 4
From: Annona muricata L. extracts decrease melanogenesis in B16F10 mouse melanoma cells
Effects of A. muricata L. extracts on MITF expression in B16F10 melanoma cell. a Effects of A. muricata L. extracts on MITF mRNA and b protein expression in B16F10 melanoma cells. *p< 0.05. To confirm the mechanisms by which A. muricata L. extracts inhibit melanogenesis, we determined MITF mRNA and protein expression levels using qRT-PCR and Western blotting analyses, respectively. These experiments demonstrated that treatments with A. muricata L. lead to decreased expression of MITF