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Fig. 1 | Biomedical Dermatology

Fig. 1

From: A brief review of pemphigus vulgaris

Fig. 1

PV on oral/skin mucosa. a: Pemphigus of the soft palate due to erosive disconnection of intraepidermal desmosomes. b: These are Pemphigus lesions of flaccid bullae that have ruptures on the upper arm. Loss of connections between keratinocytes due to autoantibodies against desmosome components render fluid buildup between these cells. They can rupture and slough away with time or manual pressure, such as seen in Nikolsky’s sign

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